WaveRider for Sentieon solution
Delivers the world’s fastest
& most efficient NGS solution
on Public Cloud
“
“ We have been impressed by the performance of the WaveRider for Sentieon solution. Early testing shows 4-5x speed-ups out-of-the-box and we expect to improve the results as we fine tune the solution. Faster processing coupled with leveraging spot instances is dramatically lowering our cloud cost too, This solution enables us to complete our NGS runs more efficiently than ever and will help elevate our research to a new level.”
- Remco Ursem, Program Leader of Bioinformatics, HZPC Research.
- Remco Ursem, Program Leader of Bioinformatics, HZPC Research.
挑战与解决方案
在公有云环境中中运行下一代测序（NGS）可能会面临一些挑战：
- 开源工具如GATK和BWA未经过优化
- 在云中部署和管理工作负载很复杂
- 云计算成本可能非常高昂
MMCloud+Sentieon解决方案能够解决这些问题。
它提供了以下改进/替代品： BWA、MEM、STAR、Minimap2、GATK、Mutect2以及面向大规模复杂流程的混合调用
挑战
- GATK/BWA虽然免费，但速度不够快
- Sentieon速度快但价格高昂
- 云平台具有可扩展性但成本高
- 优化NGS资源很困难
方案
- MMCloud加速云上的Sentieon
- MMCloud大幅降低Sentieon在云上的成本
- MMCloud包含Sentieon许可证
- MMCloud自动优化NGS工作负载的资源
SentieonKnow more about what Sentieon can do
BAM Process
Germline Variant Calling
Somatic Variant Calling
RNA Variant Calling
VCF Filtering
Long Reads
QC Statistics
MMCloud WaveRider for Sentieon Solution
- ACCELERATES NGS workloads by 10x compared to Open Source software
- REDUCES Cloud Cost by order of Magnitude
- AUTOMATES deployment workloads in the Cloud
SentieonMMCloud WaveRider for Sentieon solution provides drop-in replacement for GATK, BWA-MEM, STAR, Minimap2, Mutect2, and large cohort joint calling to do:
BAM Process
Germline Variant Calling
Somatic Variant Calling
RNA Variant Calling
VCF Filtering
Long Reads
QC Statistics
WaveRider for Sentieon solution is easy to use:
- 1Deploy MMCloud15~30 min
- 2Choose Sentieon pipeline script or provide your own script
- 3Launch Sentieon workload via MMCloud1 min
WaveRider for Sentieon Benchmark Results
Whole Genome Sequencing (WGS) Benchmark:
Baseline: Sentieon on AWS using On-demand instancevsWaveRider for Sentieon using On-demand instances
Benchmark Details
WaveRider for Sentieon - WaveWatcher Screenshots
Summary
